Dr. Tina Sampalis, Vice President of Research and Development for Neptune Technologies and Bioresources Inc., offers these dosage suggestions:

• If you're petite: start with a loading dose of 2 gelcaps (1 gram) per day for the first 2 weeks, then 1 gelcap (500 mg)/day for maintenance.
• If you're of average weight: a loading dose 3 gelcaps (1.5 grams)/day for the first 14-30 days, then 2 gelcaps (1 gram)/day for maintenance.
• If you're larger with a Body Mass Index (BMI) under 33: 3 gelcaps (1.5 grams)/day for the first 30 days, then 2 gelcaps (1 gram)/day.
• If your BMI is over 33, 3 gelcaps (1.5 grams)/day continuously.

As mentioned, dosage recommendations are also condition-specific. For example:

• Cholesterol Study Dosages. In a randomized 3-month study, 120 patients with blood cholesterol levels between 194-348 mg/dL were given a BMI-dependent daily dosage of 2-3 g NKO (Group A); 1.1-5g/day (Group B); and 3g/day fish oil containing 180 mg EPA and 120 mg DHA per gram (Group C). At both lower and equal doses, NKO was significantly more effective than fish oil for the reduction of glucose, triglyceride and LDL levels.
• Chronic Inflammation Study Dosages. A 30-day, randomized, double blind, placebo-controlled study was conducted to evaluate the effects of NKO on C-reactive protein (CRP) in 90 patients with high CRP and chronic inflammation due to cardiovascular disease and/or rheumatoid arthritis and/or osteoarthritis. Group A received 300 mg NKO daily and Group B, the placebo. Study results clearly indicated that only 300 mg NKO daily significantly inhibits inflammation and reduces arthritic symptoms within a short treatment period of 7-14 days.